MyBioSource.com's CSTF1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunocytochemistry, Immunofluorescence, and Western Blot. The CSTF1 Antibody was generated using CSTF1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA.
Subunit Structure: Homodimer. The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). Interacts directly with CSTF3. Interacts with BARD1.
Post-translational Modifications: The N-terminus is blocked.
Similarity: The WD6 domain is required for interaction with BARD1. WD domains are responsible for interaction with CSTF3.N-terminus mediates homodimerization